Educations / Professional Experience

Educations

2016/09-2021/09

Double Ph.D.

• Institute of Molecular and Cellular Biology, National Tsing Hua University, Taiwan
• Graduate School of Science, Osaka University, Japan

Current Position

2026/08-present

Assistant Professor, Institute of Molecular Medicine (IMM), College of Medicine, National Cheng Kung University (NCKU), Tainan, Taiwan

Professional Experience

2021/10-2026/07

Postdoctoral Researcher, Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan

Expertise /Research Interests

Protein structure, cellular metabolism, and molecular mechanisms of cancer

Research Interests

My research focuses on elucidating how cancer cells reprogram metabolism and organelle dynamics to adapt to cellular stress. By integrating structural biology, cancer metabolism, and molecular and cellular biology, my laboratory investigates the mechanisms underlying cancer progression at the protein and subcellular organelle levels, including mitochondria and lipid droplets. We combine protein structural analysis, fluorescence microscopy, cellular functional assays, and multi-omics approaches to uncover how disease-associated proteins and molecular interactions regulate cancer cell survival and vulnerabilities. Ultimately, our goal is to translate these mechanistic insights into structure-guided strategies for cancer targeting and therapeutic development, thereby identifying novel molecular targets and opportunities for precision cancer intervention.

Research

Directions

1. Cancer vulnerability regulated by metabolic reprogramming.
2. Structural and functional analysis of metabolic enzymes.