Educations / Professional Experience

Educations

1980/8-1984/12

University of South Carolina, Ph.D.

1974/9-1978/6

National Taiwan Normal University, B.S.

Current Position

2022/08-

Distinguished Professor, Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University.

1991/01-

Consultant, GlycoMed Research Incorporated, Hastings on Hudson, NY

1989/09-

Adjunct Associate Professor, Medical University of South Carolina, College of Dental Medicine

Professional Experience

2010/8-2016/7

Institute director, Institute of Molecular Medicine, College of Medicine, National Cheng Kung University

2006/9-2022/7

Distinguished Professor, Institute of Molecular Medicine, College of Medicine, National Cheng Kung University

1995/7-2005/12

Associate Scientist and Laboratory Director, Guthrie Research Institute, Laboratory of Molecular Immunology & Protein/Peptide Microsequencing Core Facility

1989/7-1995/6

Assistant Scientist and Laboratory Director, Guthrie Research Institute, Laboratory of Molecular Immunology & Protein/Peptide Microsequencing Core Facility

1996/3-2006/8

Adjunct Research Associate Professor, Upstate Medical University at Syracuse, Department of Immunology and Microbiology & Integrated Medicine

1987/1-1989/6

Instructor, University of Massachusetts Medical Center, Department of Biochemistry

1985/1-1986/12

Post Doctoral Fellow, The Samuel Roberts Noble Foundation, Immunology Section

1982

Teaching Assistant of Dental Microbiology for one semester, Medical Univ. of South Carolina, Dept. of Basic & Clinical Immunology & Microbiology

1978/7-1980/7

Teaching Assistant, National Taiwan Normal Univ., Department of Biology

1977 winter

Research Assistant, Tungkang Marine Laboratory, Tungkang, Taiwan

Expertise /Research Interests

Signal transduction, Apoptosis

Research Interests

Signal transduction, Apoptosis

Research

Directions

1. Mechanism of apoptosis:  Role of WW domain-containing oxidoreductase WOX1 in regulation of mitochondrial apoptosis and cancerous progression.  We discovered this gene in year 2000, and have been the leader in the field (research supported by NSC, NHRI, & Dept. Defense USA).

2. Signaling transduction and neurodegeneration: Elucidating signaling network that controls neurodegeneration (research supported by NSC & NHRI).

3. Naturally occurring small-size anticancer proteins: Role of Zfra in protein turnover and tumor progression (research supported by Dept. Defense USA & DOH, Taiwan).