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劉紋君 publication(en)

Wen-Chun,Liu

Publications

A. Refereed Papers

  1. Tseng CW, Liu WC, Ko PH, Chen YC, Tseng KC, Chang TT:  The Predictive Role of Hepatitis B Biomarkers on HBV Reactivation following Direct-Acting Antiviral Therapy in HBV/HCV Coinfected Patients. Viruses 2022, 14(8), 1812. doi: 10.3390/v14081812
  2. Tseng CW, Liu WC, Chen CY, Chang TT, Tseng KC. Impact of HCV viremia on HBV biomarkers in patients coinfected with HBV and HCV. BMC Infect Dis. 2022 Apr 9;22(1):351. doi: 10.1186/s12879-022-07326-1. PMID: 35397497; PMCID: PMC8994285.
  3. Wu IC, Liu WC*, Chiu YC, Chiu HC, Cheng PN, Chang TT. Clinical Implications of Serum Hepatitis B Virus Pregenomic RNA Kinetics in Chronic Hepatitis B Patients Receiving Antiviral Treatment and Those Achieving HBsAg Loss. Microorganisms. 2021 May 26;9(6):1146. doi: 10.3390/microorganisms9061146. PMID: 34073483; PMCID: PMC8229518. (Co-first author)
  4. Liu WC*, Wu IC, Chiu YC, Tseng KC, Chen CY, Chiu HC, Cheng PN, Chang TT. Genotyping of immune-related loci associated with delayed HBeAg seroconversion in immune-active chronic hepatitis B patients. Antiviral Res. 2020 Jan 28:104719. doi: 10.1016/j.antiviral.2020.104719. [Epub ahead of print] PubMed PMID: 32004619. 此篇為第一作者。
  5. Lin TC, Liu WC, Hsu YH, Lin JJ, Chiu YC, Chiu HC, Cheng PN, Chen CY, Chang TT, Wu IC. Insulin Resistance Associated Disorders Pivoting Long-Term Hepatitis B Surface Antigen Decline During Entecavir Therapy. J Clin Med. 2019 Nov 6;8(11). pii: E1892. Doi 10.3390/jcm8111892. PubMed PMID: 31698809; PubMed Central PMCID: PMC6912775.
  6. Wu IC, Liu WC*, Chang TT. Applications of next-generation sequencing analysis for the detection of hepatocellular carcinoma-associated hepatitis B virus mutations. J Biomed Sci. 2018 Jun 2;25(1):51. doi: 10.1186/s12929-018-0442-4. Review. PubMed PMID: 29859540; PubMed Central PMCID: PMC5984823.  此篇為共同第一作者。
  7. Lin TC, Chiu YC, Chiu HC, Liu WC, Cheng PN, Chen CY, Chang TT, Wu IC. Clinical utility of hepatitis B surface antigen kinetics in treatment-naïve chronic hepatitis B patients during long-term entecavir therapy. World J Gastroenterol. 2018 Feb 14;24(6):725-736. doi: 10.3748/wjg.v24.i6.725. PubMed PMID: 29456411; PubMed Central PMCID: PMC5807675.
  8. Liu WC*, Wu IC, Lee YC, Lin CP, Cheng JH, Lin YJ, Yen CJ, Cheng PN, Li PF, Cheng YT, Cheng PW, Sun KT, Yan SL, Lin JJ, Yang JC, Chang KC, Ho CH, Tseng VS, Chang BC, Wu JC, Chang TT. Hepatocellular carcinoma-associated single-nucleotide variants and deletions identified by the use of genome-wide high-throughput analysis of hepatitis B virus. J Pathol. 2017 Oct;243(2):176-192. doi: 10.1002/path.4938. Epub 2017 Aug 17. Review. PubMed PMID: 28696069. 此篇為第一作者。
  9. Cheng JH, Liu WC, Chang TT, Hsieh SY, Tseng VS. Detecting exact breakpoints of deletions with diversity in hepatitis B viral genomic DNA from next-generation sequencing data. Methods. 2017 Oct 1;129:24-32. doi: 10.1016/j.ymeth.2017.08.005.Epub 2017 Aug 10. PubMed PMID: 28802713.
  10. Ho CH, Tsai HW, Lee CY, Huang LJ, Chien RN, Wu IC, Chiu YC, Liu WC, Cheng PN, Chang TT, Chen SH. Favorable Response to Long-term Nucleos(t)ide Analogue Therapy in HBeAg-positive Patients with High Serum Fucosyl-Agalactosyl IgG. Sci Rep. 2017 May 16;7(1):1957. doi: 10.1038/s41598-017-02158-5. PubMed PMID: 28512353; PubMed Central PMCID: PMC5434008.
  11. Cheng CP, Lan KL, Liu WC, Chang TT, Tseng VS. DeF-GPU: Efficient and effective deletions finding in hepatitis B viral genomic DNA using a GPU architecture. Methods. 2016 Dec 1;111:56-63. doi: 10.1016/j.ymeth.2016.07.020. Epub 2016 Jul 30. PubMed PMID: 27480381.
  12. Liu WC*, Lin CP, Cheng CP, Ho CH, Lan KL, Cheng JH, Yen CJ, Cheng PN, Wu IC, Li IC, Chang BC, Tseng VS, Chiu YC, Chang TT. Aligning to the sample-specific reference sequence to optimize the accuracy of next-generation sequencing analysis for hepatitis B virus. Hepatol Int. 2016 Jan;10(1):147-57. doi: 10.1007/s12072-015-9645-x. Epub 2015 Jul 25. PubMed PMID: 26208819; PubMed Central PMCID: PMC4722079. 此篇為第一作者。
  13. Ho CH, Chien RN, Cheng PN, Liu CK, Su CS, Wu IC, Liu WC, Chen SH, Chang TT. Association of serum IgG N-glycome and transforming growth factor-β1 with hepatitis B virus e antigen seroconversion during entecavir therapy. Antiviral Res. 2014 Nov;111:121-8. doi: 10.1016/j.antiviral.2014.09.011. Epub 2014 Sep 28. PubMed PMID: 25260899.
  14. Ho CH, Chien RN, Cheng PN, Liu JH, Liu CK, Su CS, Wu IC, Li IC, Tsai HW, Wu SL, Liu WC, Chen SH, Chang TT. Aberrant serum immunoglobulin G glycosylation in chronic hepatitis B is associated with histological liver damage and reversible by antiviral therapy. J Infect Dis. 2015 Jan 1;211(1):115-24. doi: 10.1093/infdis/jiu388. Epub 2014 Jul 10. PubMed PMID: 25015948.
  15. Tseng KC, Chen CY, Tsai HW, Chang TT, Chuang WL, Hsu PI, Liu WC, Cheng PN. Efficacy of entecavir in chronic hepatitis B patients with persistently normal alanine aminotransferase: randomized, double-blind, placebo-controlled study. Antivir Ther. 2014;19(8):755-64. doi: 10.3851/IMP2754. Epub 2014 Feb 28. PubMed PMID: 24583931.
  16. Cheng CP, Lee PF, Liu WC, Wu IC, Chin CY, Chang TT, Tseng VS. Analysis of precore/core covariances associated with viral kinetics and genotypes in hepatitis B e antigen-positive chronic hepatitis B patients. PLoS One. 2012;7(2):e32553. doi: 10.1371/journal.pone.0032553. Epub 2012 Feb 27. PubMed PMID: 22384271; PubMed Central PMCID: PMC3288105.
  17. Sun HY, Ou NY, Wang SW, Liu WC, Cheng TF, Shr SJ, Sun KT, Chang TT, Young KC. Novel nucleotide and amino acid covariation between the 5'UTR and the NS2/NS3 proteins of hepatitis C virus: bioinformatic and functional analyses. PLoS One. 2011;6(9):e25530. doi: 10.1371/journal.pone.0025530. Epub 2011 Sep 28. PubMed PMID: 21980483; PubMed Central PMCID: PMC3182228.
  18. Cheng PN, Liu WC, Tsai HW, Wu IC, Chang TT, Young KC. Association of intrahepatic cccDNA reduction with the improvement of liver histology in chronic  hepatitis B patients receiving oral antiviral agents. J Med Virol. 2011 Apr;83(4):602-7. doi: 10.1002/jmv.22014. PubMed PMID: 21328373.
  19. Tseng KC, Cheng PN, Wu IC, Chang CK, Chou AL, Liu WC, Chang TT. HBV DNA level as an important determinant of E antigen seroconversion of chronic hepatitis B during adefovir dipivoxil therapy. Hepatogastroenterology. 2009 May-Jun;56(91-92):813-8. PubMed PMID: 19621708.
  20. Liu WC*, Lindh M, Buti M, Phiet PH, Mizokami M, Li HH, Sun KT, Young KC, Cheng PN, Wu IC, Chang TT. Genotyping of hepatitis B virus--genotypes a to g by multiplex polymerase chain reaction. Intervirology. 2008;51(4):247-52. doi: 10.1159/000156484. Epub 2008 Sep 24. PubMed PMID: 18812698. 此篇為第一作者。
  21. Liu WC*, Phiet PH, Chiang TY, Sun KT, Hung KH, Young KC, Wu IC, Cheng PN, Chang TT. Five subgenotypes of hepatitis B virus genotype B with distinct geographic and virological characteristics. Virus Res. 2007 Nov;129(2):212-23. Epub 2007 Sep 7. PubMed PMID: 17825452. 此篇為第一作者。
  22. Wu IC, Chow NH, Cheng PN, Liu WC, Young KC, Chang WL, Chen CY, Tseng KC, Chang TT. Characterization of viral kinetics in patients with hepatitis B e antigen-positive chronic hepatitis B. J Med Virol. 2007 Jun;79(6):663-9. PubMed PMID: 17457902.
  23. Liu WC*, Mizokami M, Buti M, Lindh M, Young KC, Sun KT, Chi YC, Li HH, Chang TT. Simultaneous quantification and genotyping of hepatitis B virus for genotypes A to G by real-time PCR and two-step melting curve analysis. J Clin Microbiol. 2006 Dec;44(12):4491-7. Epub 2006 Oct 4. PubMed PMID: 17021067; PubMed Central PMCID: PMC1698380. 此篇為第一作者。
  24. Young KC, Lindsay KL, Lee KJ, Liu WC, He JW, Milstein SL, Lai MM. Identification of a ribavirin-resistant NS5B mutation of hepatitis C virus during ribavirin monotherapy. Hepatology. 2003 Oct;38(4):869-78. PubMed PMID: 14512874.

B.  Conference papers

a. International Conference

  1. Wen-Chun Liu, Ting-Tsung Chang. Single Nucleotide Variants Associated with Viral Replication Efficiency Identified Using Genome-Wide Next-Generation Sequencing Analysis of Hepatitis B Virus. The 5th International Symposium on Infectious Disease and Signal Transduction /2015 Taiwan-Japan Joint Symposium on Cell Signaling and Gene Regulation. Nov. 14th -15th, 2015
  2. Ting-Tsung Chang, Wen-Chun Liu. Characteristics of HBV Quasispecies Associated with Hepatocellular Carcinoma by Next-Generation Sequencing and Database Meta-Analysis The 4th International Symposium on Infectious Disease and Signal Transduction/ 2014 Taiwan-Japan Joint Symposium on Cell Signaling and Gene Regulation. Nov. 1st -2nd, 2014.
  3. Wen-Chun Liu, I-Chin Wu, Ting-Tsung Chang. Mapping of PreS-Deletion Within the Hepatitis B Virus Genome Among Chronic Hepatitis B Patients With Hepatocellular Carcinoma by Next-Generation Sequencing. The 4th International Symposium on Infectious Disease and Signal Transduction/ 2014 Taiwan-Japan Joint Symposium on Cell Signaling and Gene Regulation. Nov. 1st -2nd, 2014.
  4. Wen-Chun Liu, Chia-Han Chan, Vincent Shin-Mu Tseng, Chia-Jui Yen, Pin-Nan Cheng, I-Chin Wu, Yen-Cheng Chiu, Yu-Ping Lin, Cheng-Hsun Ho, Ting-Tsung Chang. Comparison of serum hepatitis B virus quasispecies in HBV-related hepatocellular carcinoma and chronic hepatitis B patients by Next-generation sequencing (NGS). The 22nd Conference of the Asian Pacific Association for the Study of the Liver. February 16-19 2012

 

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