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張南山 Nan-Shan Chang  

Nan-Shan Chang

張南山教授(Nan-Shan Chang)

E-mailwox1world@mail.cmu.edu.tw

電話:04-22053366 #8212

辦公室位置 : 立夫教學大樓7

 

學經歷

學歷

1980/8-1984/12

美國南卡羅萊納大學基礎與臨床微生物與免疫學博士

1974/9-1978/6

國立台灣師範大學學士

現職

2022/08-

中國醫藥大學生物醫學研究所特聘教授

1991/01-

Consultant, GlycoMed Research Incorporated, Hastings on Hudson, NY

1989/09-

Adjunct Associate Professor, Medical University of South Carolina, College of Dental Medicine

經歷

2010/08-2016/07

國立成功大學醫學院分子醫學研究所所長

2006/09-2022/07

國立成功大學醫學院分子醫學研究所教授(特聘教授)

1995/7-2005/12

Associate Scientist and Laboratory Director, Guthrie Research Institute, Laboratory of Molecular Immunology & Protein/Peptide Microsequencing Core Facility

1989/7-1995/6

Assistant Scientist and Laboratory Director, Guthrie Research Institute, Laboratory of Molecular Immunology & Protein/Peptide Microsequencing Core Facility

1996/3-2006/8

Adjunct Research Associate Professor, Upstate Medical University at Syracuse, Department of Immunology and Microbiology & Integrated Medicine

1987/1-1989/6

Instructor, University of Massachusetts Medical Center, Department of Biochemistry

1985/1-1986/12

Post Doctoral Fellow, The Samuel Roberts Noble Foundation, Immunology Section

1982

Teaching Assistant of Dental Microbiology for one semester, Medical Univ. of South Carolina, Dept. of Basic & Clinical Immunology & Microbiology

1978/7-1980/7

Teaching Assistant, National Taiwan Normal Univ., Department of Biology

1977 winter

Research Assistant, Tungkang Marine Laboratory, Tungkang, Taiwan

 

專長/研究興趣

細胞訊息傳遞、細胞凋亡

興趣

細胞訊息傳遞、細胞凋亡

方向

目前的研究方向主要有三:

1.  Mechanism of apoptosis:  Role of WW domain-containing oxidoreductase WOX1 in regulation of mitochondrial apoptosis and cancerous progression.  We discovered this gene in year 2000, and have been the leader in the field (research supported by NSC, NHRI, & Dept. Defense USA).

2.  Signaling transduction and neurodegeneration: Elucidating signaling network that controls neurodegeneration (research supported by NSC & NHRI).

3.  Naturally occurring small-size anticancer proteins: Role of Zfra in protein turnover and tumor progression (research supported by Dept. Defense USA & DOH, Taiwan).

                

  

 

榮譽獎項

2011

美國實驗生物醫學協會傑出科學家獎

2010

DOD Neurofibrometosis Research Award

2008

DOD Breast Cancer Concvept Award

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