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IMM學生專題報告準則

 

2023春季(111-2)

2022/11/24修訂 

文章選擇和繳交:

  • 你的專題報告務必是以報告日期一年內發表且IF>5的文章 (Published after Jan, 2022)
  • 同學所選的文章必須與你的研究領域無直接相關
  • 碩一同學可選與你的研究領域有關的文章但需要指導教授的同意

繳交時間與細節:

  • 碩一同學繳交時間皆為2023/01/09
  • 繳交時,需將你所選文章標題連結網emailIMM網站管理者以及你的講評老師。
  • 同學交一份紙本文章林世杰老師,碩一同學則交一份紙本文章林世杰及橋本昌征老師(文章第一頁上請寫明你的名字年級報告日期)

講評老師:

  • 負責教師會出面邀請碩二同學講評老師(包括本所或外所專任及合聘老師,其專業及研究領域符合你所選文章的領域)
  • 碩一同學的指導教授為講評老師。 

英文摘要繳交時間與撰寫:

  • 依所選的文章,同學必須以Word的格式自寫一頁英文摘要(可參考第二頁的摘要範例)
  • 專題報告的一星期前必須將英文摘要email給講評老師、負責老師及IMM網站管理。若遲交,你的學期分數將扣總平均10

報告前一個週四下午5:00前交摘要到IMM網站管理信箱:imm3556@gmail.com

報告時間準備準則評分原則

  • 報告時間不得超過35分鐘
  • 準備30-40投影片簡報,首先以一張投影片簡要地介紹該文章通訊作者及其近5年的研究興趣,然後依文章的背景、結果(含方法與重要的材料) 、討論的順序報告。
  • 同學英文方式報告。
  • 碩一同學以中文(但鼓勵以英文)方式報告請以一張投影片將文章的重點做圖示摘要,並以英文做2-3分鐘的介紹。
  • 以英文報告的同學,在介紹通訊作者前,請以一張投影片做圖示摘要,並以中文做2-3分鐘的總結。
  • “Tips for Seminar Presentation”列於第六頁
  • 報告的評分原則列於第三頁(中文版)與第五頁(英文版)

聯絡資訊:

 

 

英文摘要範例

Signaling Kinase AMPK Activates Stress-Promoted Transcription via Histone H2B Phosphorylation

D. Bungard, et al. Science 329:1201-1205, 2010

Presenter: Shang-Yu Yeh                            Date/Time: 2010/11/18, 16:10 -17:00

Commentator: Dr. Wu-Chou Su              Location: Room 601, Med College Building

Background: The adenosine monophosphate-activated protein kinase (AMPK) is an intracellular energy sensor that maintains the energy balance and becomes phosphorylated at Threonine172 in response to changes in cellular ATP levels. Activated AMPK acts as an inducer or suppressor of apoptosis, depending on energy stress and certain functional tumor suppressor genes. However, the details of regulated mechanism remain unclear.

Objective/Hypothesis: To investigate the underlying mechanisms by which cells respond to stresses to regulate p53-dependent genes and promote survival through the LKB1-AMPK pathway.

Results: In the study, mouse embryonic fibroblasts (MEFs) were treated with a wide variety of stresses. When cells received stress signals, liver kinase B1 (LKB1, one of three upstream AMPK kinases), activated and bound to AMPK. Subsequently, the LKB-AMPK complex was recruited to nuclei and interacted with specific promoters in a p53-dependent fashion. The LKB1-AMPK complex then phosphorylated histone H2B at serine36 site, and regulated the expression of p53-dependent genes, such as p21. The p21 protein can stop or retard cell cycle till the cells can develop normally. A similar epigenetic mechanism was also observed in HCT116 and 293T cells. Therefore, it may become novel therapeutic targets for human diseases.

Conclusion: The authors suggest that modification of H2B by AMPK may be a general stress-response pathway to tune specific transcriptional responses to regulate cellular metabolism and promote cell survival.

References:

1.  D. Grahame Hardie, AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nature Rev. Mol. Cell Biol. 8:774-785, 2077.

2.  R.G. Jones et al., AMP-activated protein kinase induces a p53-dependent metabolic

 

專題報告評分原則

2022/11/24

一、出勤和守時 (10%)

每學期需參加所有的專題演講,報告的學生有任何變動必須至少提前一周與課程協調負責老師討論未經負責老師同意不得任意變更或選擇不報告無故變更者將嚴重扣分。病假請附醫師證明或是醫療支付證明,若是任何無故缺席或遲到將扣分


二、摘要和簡報 (60%)

       A. 摘要撰寫與內容 (20%)

           (1) 背景

           (2) 假設/目標

           (3) 研究結果,包括方法及途徑

           (4) 結論和意義

       B. 報告內容和組織 (40%)

           (1) 簡介
           (2)
理解方法的能力

           (3) 解釋數據的能力

           (4) 整體組織能力及表達能力

       C. 報告 (40%)

           (1) 口語表現

           (2) 投影片內容製作能力

           (3) 表達原由,解說能力

(4) 報告時間的控制(不超過35分鐘 不宜短於25分鐘)

三、內容提問 (15%)

        每學期你必須在至少5主題的內容參與發問

四、出席學校辦的演講 (15%)

        我們要求學生參加至少5個演講 (以簽到表為準)

五、額外獎勵 (5%)

       碩一同學若用英文報告可多得5分的報告成績

 

Guidelines for IMM Student Seminar

Spring 2023

2022/11/24

Article selection & submission

Article selection: You are encouraged to select a recent article with IF>5 (e.g., published after January 2021) that is NOT directly related to your research field. The first-year students are allowed to select the recent high impact publication related to his or her thesis research topics.

Submission time: You MUST submit the title and the URL connection address of the article of your choice to the IMM website manager (IMM: imm3556@gmail.com ). At the same time, each student needs to send a hard copy of your article to Professors Shih-Chieh Lin and Masayuki Hashimoto. The submission deadline for the all of the students is no later than January 9, 2023.

Abstract format and submission

Abstract format: Please use your own words to write ONLY one page of abstract according to the suggested format below.

Submission to whom:

  1. If you are a 1st year student, please email your abstract to Professor Shih-Chieh Lin (jaylin@mail.ncku.edu.tw)/Professor Masayuki Hashimoto. (hashmate@mail.ncku.edu.tw), your commentator, and IMM website manager at least one week prior to your seminar date.
  2. If you are a 2nd year student, please email your abstract to Professor Shih-Chieh Lin  (jaylin@mail.ncku.edu.tw), your commentator, and IMM website manager at least one week prior to your seminar date.
  3. Any late submission will result in 10 points deduction from your final grade.

PowerPoint slides

Preparation: You have to present your article no more than 35 minutes in PowerPoint format. Therefore, you only need to prepare 30-40 slides for your presentation considering one slide per minute.

Contents: Please prepare your slides in the order of Background, Hypothesis, Methods/Results, and Discussion/Conclusion. Before paper presentation, you should prepare one slide to briefly introduce the research interest of the corresponding author in the last 5 years.

Language of presentation: All student in the second year or higher must present your article in English.  To begin your English presentation, please give a 2~3 min summary of key points of the paper in Mandarin. For students in the first year, you are required to give a short summary of the key points of the paper in English.