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黃湘琦publication

研究成果 ( Publications) 

A. Peer-Reviewed Publications

  1. Huang HC* , Lobo V, Schön K, Nowak I, Westholm JO, Fernandez C, Patel A, Wiel C, Sayin V, Anastasakis DG, Angeletti D# , Sarshad AA*# (2024). Nuclear RNAi Modulates Influenza A Virus Infectivity By Downregulating Type-I Interferon Response. bioRxiv 2024.03.07.583365. In second round of review at Nature Communications. *Co-corresponding author (2023 IF: 14.7).

  2. Lobo V, Nowak I, Fernandez C, Iris Correa Muler A, Westholm JO, Huang HC, Fabrik I, Huynh HT, Kanik M, Härtlova A, Benhalevy D, Angeletti D, Sarshad A. Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference. Nucleic Acids Research, Jul 12:gkae589. (2024). https://doi: 10.1093/nar/gkae589 (2023 IF:16.6).

  3. Lobo V, Shcherbinina E, Westholm JO, Nowak I, Huang HC, Angeletti D, Anastasakis DG, Sarshad A. Integrative transcriptomic and proteomic profiling of the effects of cell confluency on gene expression. Scientific Data 11, 617 (2024). https://doi.org/10.1038/s41597-024-03465-z (2024) (2023 IF:5.8).

  4. Huang HC and Angeletti D. Monoclonal antibodies lock down SARS-CoV-2 spike. Trends in Immunology 2023 Oct 5 (2023 IF:16.8).

  5. Huang HC, Wang SH, Fang GC, Chou WC, Liao CC, Sun CP, Jan JT, Ma HH, Ko HY, Ko YA Chiang MT, Liang JJ, Kuo CT, Lee TA, Diego Morales‐Scheihing DM, Shen CY, Chen SY, McCullough LD, Cui L, Wernig G, Tao MH, Lin YL, Chang YM, Wang SP, Lai YJ, Li CW. Upregulation of PD‐L1 by SARS‐CoV‐2 promotes immune evasion. Journal of Medical Virology. 2023 Jan 7 (2023 IF:12.7).

  6. Wang SH, Chou WC, Huang HC, Lee TA, Hsiao TC, Wang LH, Huang KB, Kuo CT, Chao CH, Chang CI, Hsu JM, Weng J, Ren N, Li FA, Lai YJ, Zhou C, Hung MC, Li CW. Deglycosylation of SLAMF7 in breast cancers enhances phagocytosis. Am J Cancer Res 2022;12(10):4721-4736 (2023 IF:5.3).

  7. Huang HC, Lai YJ, Liao CC, Yang WF, Huang KB, Lee IJ, Chou WC, Wang SH, Wang LH, Hsu JM, Sun CP, Kuo CT, Wang J, Hsiao TC, Yang PJ, Lee TA, Huang W, Li FA, Shen CY, Lin YL, Tao MH, Li CW. Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro. EBioMedicine. 2021 Dec;74:103712. doi: 10.1016/j.ebiom.2021.103712. Epub 2021 Nov 25 (2023 IF:11.1).

  8. Huang HC, Liao CC, Wang SH, Lee IJ, Lee TA, Hsu JM, Kuo CT, Wang J, Hsieh WC, Chang SJ, Chen SY, Tao MH, Lin YL, Lai YJ, Li CW. Hyperglycosylated spike of SARS-CoV-2 gamma variant induces breast cancer metastasis. Am J Cancer Res. 2021 Oct 15;11(10):4994-5005 (2023 IF:5.3).

  9. Hsieh WC, Lai EY, Liu YT, Wang YF, Tzeng YS, Cui L, Lai YJ, Huang HC, Huang JH, Ni HC, Tsai DY, Liang JJ, Liao CC, Lu YT, Jiang L, Liu MT, Wang JT, Chang SY, Chen CY, Tsai HC, Chang YM, Wernig G, Li CW, Lin KI, Lin YL, Tsai HK, Huang YT, Chen SY. NK cell receptor and ligand composition influences the clearance of SARS-CoV-2. J Clin Invest. 2021 Nov 1;131(21):e146408. doi: 10.1172/JCI146408 (2023 IF:15.9).

  10. Lai YJ, Chao CH, Liao CC, Lee TA, Hsu JM, Chou WC, Wang J, Huang HC, Chang SJ, Lin YL, Li CW. Epithelial-mesenchymal transition induced by SARS-CoV-2 required transcriptional upregulation of Snail. Am J Cancer Res. 2021 May 15;11(5):2278-2290 (2023 IF:5.3).

  11. Huang HC, Bi-He Cai, Ching-Shu Suen, Hsueh-Yi Lee, Ming-Jing Hwang, Fu-Tong Liu, Reiji Kannagi BGN/TLR4/NF-κB Mediates Epigenetic Silencing of Immunosuppressive Siglec Ligands in Colon Cancer Cells (2020). Cells. 2020, 9, 397; doi:10.3390/cells9020397 (2023 IF:6).

  12. Cai BH, Lee HY, Chou CK, Wu PH, Huang HC, Chao CC, Chung HY, Kannagi R. SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1- STAT3 Signaling in Human ES Cells. Cells. 2020 Jan 10;9(1). pii: E177. doi: 10.3390/cells9010177 (2023 IF:6).

  13. Cai BH, Lee HY, Chou CK, Wu PH, Huang HC, Chao CC, Chung HY, Kannagi R*. Chen JY*. Family Structure and Function in Non-Canonical Response Element Binding and Activation. (2019) Int. J. Mol. Sci., 20, 3681. doi: 10.3390/ijms20153681 (2023 IF:5.6).

  14. Cai BH, Wu PH, Chou CK, Huang HC, Chao CC, Chung HY, Lee HY, Chen JY, Kannagi R. Synergistic activation of the NEU4 promoter by p73 and AP2 in colon cancer cells. Sci Rep. 2019 Jan 30;9(1):950. doi: 10.1038/s41598-018-37521-7 (2023 IF:3.8).

  15. Huang HC, Chao CC, Wu PH, Chung HY, Lee HY, Suen CS, Hwang MJ, Cai BH, Kannagi Epigenetic silencing of the synthesis of immunosuppressive Siglec ligand glycans by NF- κB/EZH2/YY1 axis in early-stage colon cancers. (2019) Biochim Biophys Acta Gene Regul Mech. 1862(2):173-183. doi: 10.1016/j.bbagrm.2019.01.002 (2023 IF:4.7).

  16. Chao CC, Wu PH, Huang HC, Chung HY, Chou YC, Cai BH, Kannagi R. Downregulation of miR199a/b-5p is associated with GCNT2 induction upon epithelial-mesenchymal transition in colon cancer. (2017) FEBS Lett. 591(13):1902-1917. doi: 10.1002/1873-3468.12685 (2023 IF:3.5).

  17. Wang CC, Huang HC (co-first author), Chen CL*, Wang PJ, Kuo CF, Lin YS, Wu JJ, Lin MT, Liu CC, Huang W, Chuang WJ. Solution structure and backbone dynamics of streptopain: insight into diverse substrate specificity. (2009) J Biol Chem. 284(16):10957-67. doi: 10.1074/jbc.M807624200 (2023 IF:4.8).

B. Books

1. R Kannagi*, BH Cai, HC Huang, K Sakuma. Regulation of cell surface glycan expression in cancer stem cells. (2016) Cancer Metastasis and Cancer Stem Cell/Niche, Bentham Science. Publisher eBook Series, pp. 24-60.

2. R Kannagi*, BH Cai, HC Huang, CC Chao, K Sakuma. Gangliosides and Tumors. (2018) Methods Mol Biol, 1804:143-171.

 

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